Bernhard K, van der Zypen E, Fankhauser F
Klin Monbl Augenheilkd. 1979 Jun;174(6):780-3.
The ultrastructural alterations of 10 pigmented rabbit irides 15 minutes to 257 days after irradiation with a xenon arc lamp were analysed. Pulse duration was varied while irradiation power was kept constant at 3.24 W. 0.32 J (= 100 ms pulse duration) were delivered to the left eye and 3.2 J (= 1 second pulse duration) to the right side. The area of damage event was considerably smaller at the lower energy level. However depth of the crater was the same at both higher and lower levels. Cells and organelles disintegrate forming lamellar structures and coarse granules. The shape of the pigment granules remains intact. Collagen fibres disintegrate into subunits loosing their periodicity. Mesenchymal cells cover the area of damage few days after irradiation at the low energy level. A thin scar remains at the impact site. High energy irradiation shifts the equilibrium towards degenerative phenomena. Secondary degenerative processes are powerful enough to induce a total decay of the iris substance. The reactivity of the iris irradiated by a xenon arc lamp thus depends from either irradiation duration, power level or from both (energy).
分析了10只色素沉着兔虹膜在氙弧灯照射后15分钟至257天的超微结构变化。脉冲持续时间可变，而照射功率保持恒定在3.24W。左眼给予0.32J（=100ms脉冲持续时间），右眼给予3.2J（=1秒脉冲持续时间）。较低能量水平下损伤区域明显较小。然而，高低能量水平下凹坑的深度相同。细胞和细胞器解体形成层状结构和粗大颗粒。色素颗粒的形状保持完整。胶原纤维解体成亚单位，失去其周期性。低能量水平照射后几天，间充质细胞覆盖损伤区域。撞击部位留下一条薄疤痕。高能量照射使平衡向退行性现象转变。继发性退行性过程足以导致虹膜物质完全衰退。因此，氙弧灯照射的虹膜反应性取决于照射持续时间、功率水平或两者（能量）。
