人体脂肪分解的调节。关于肾上腺素能受体作用的体内观察。
Regulation of human lipolysis. In vivo observations on the role of adrenergic receptors.
作者信息
Burns T W, Mohs J M, Langley P E, Yawn R, Chase G R
出版信息
J Clin Invest. 1974 Jan;53(1):338-41. doi: 10.1172/JCI107556.
Abstract
Changes in the plasma free fatty acids of a pancreatectomized subject and in free fatty acids and insulin in 10 normal subjects in response to the in vivo infusion of epinephrine alone, epinephrine plus phentolamine, and epinephrine plus propranolol indicate that both alpha and beta adrenergic receptors are present in human adipose tissue. Under the experimental conditions used, adipose tissue appeared to be more responsive to epinephrine than did the cardiovascular system.
摘要
胰腺切除受试者的血浆游离脂肪酸以及10名正常受试者的游离脂肪酸和胰岛素在分别单独体内输注肾上腺素、肾上腺素加酚妥拉明、肾上腺素加普萘洛尔后的变化表明，人类脂肪组织中同时存在α和β肾上腺素能受体。在所采用的实验条件下，脂肪组织对肾上腺素的反应似乎比心血管系统更为敏感。
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