• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Identification of two new metabolites of hydralazine from human urine.

作者信息

Zak S B, Gilleran T G, Karliner J, Lukas G

出版信息

J Med Chem. 1974 Mar;17(3):381-2. doi: 10.1021/jm00249a035.

DOI:10.1021/jm00249a035
PMID:4811243
Abstract
摘要

相似文献

1
Identification of two new metabolites of hydralazine from human urine.
J Med Chem. 1974 Mar;17(3):381-2. doi: 10.1021/jm00249a035.
2
Identification of 3-methyl-s-triazolo(3,4-alphathalazine, a human hydralazine metabolite, by gas chromatography-mass spectrometry.
Arzneimittelforschung. 1973 Aug;23(8):1028-9.
3
3-Hydroxymethyl-s-triazolo[3,4-a]phthalazine, a novel urinary hydralazine metabolite in man.
J Med Chem. 1975 Oct;18(10):1031-3. doi: 10.1021/jm00244a018.
4
Determination of hydralazine metabolites: 4-hydrazino-phthalazin-1-one and n-acetylhydrazinophthalazin-1-one by gas chromatography and s-triazolo[3,4-alpha]phthalazine and phthalazinone by high-performance liquid chromatography.
J Chromatogr. 1980 Aug 8;183(2):167-73. doi: 10.1016/s0378-4347(00)81690-4.
5
Studies in the rabbit on 3-methyltriazolophthalazine, an acetylated metabolite of hydralazine. Evidence for an alternative route of formation.
Drug Metab Dispos. 1980 Mar-Apr;8(2):73-6.
6
Identification and quantitation of hydrazine in the urine of patients treated with hydralazine.
Clin Pharmacol Ther. 1979 Jul;26(1):81-8. doi: 10.1002/cpt197926181.
7
Metabolism of hydralazine in man.
Arzneimittelforschung. 1977;27(12):2388-95.
8
Metabolism and disposition of hydralazine-14C in man and dog.
Drug Metab Dispos. 1974 Jul-Aug;2(4):351-60.
9
Hydralazine urinary metabolites in systemic lupus erythematosus.
Arthritis Rheum. 1973 Mar-Apr;16(2):217-20. doi: 10.1002/art.1780160212.
10
Metabolites of 3-hydrazino-6-[bis-(2-hydroxyethyl)amino]pyridazine dihydrochloride in rat urine.
Eur J Drug Metab Pharmacokinet. 1979;4(1):29-33. doi: 10.1007/BF03189396.

引用本文的文献

1
Further evidence for an acetylator phenotype difference in the metabolism of hydralazine in man.关于人体内肼屈嗪代谢中乙酰化表型差异的进一步证据。
Br J Clin Pharmacol. 1981 Apr;11(4):345-51. doi: 10.1111/j.1365-2125.1981.tb01131.x.
2
Pharmacokinetics of oral hydralazine in chronic heart failure.口服肼屈嗪在慢性心力衰竭中的药代动力学。
Eur J Clin Pharmacol. 1983;25(4):467-73. doi: 10.1007/BF00542113.
3
Studies on hydralazine. III. Bioavailability of hydralazine in man.
Eur J Clin Pharmacol. 1976;10(6):395-401. doi: 10.1007/BF00563075.
4
Disposition and metabolism of 3-hydrazino-6-[N,N-bis(2-hydroxyethyl)amino] pyridazine dihydrochloride in man.
Eur J Drug Metab Pharmacokinet. 1979;4(2):75-82. doi: 10.1007/BF03189404.