Garwicz S
Lancet. 1975 Apr 26;1(7913):956-7. doi: 10.1016/s0140-6736(75)92012-7.
It is proposed that atypical spherocytosis is a result of severe spherocytosis combined with splenic dysfunction. The spleen exercises a "conditioning" effect on the red blood-cell but is insufficient in the "culling" and "pitting" functions. As a result, a large population of severely damaged erythrocytes is circulating in the peripheral blood giving rise to atypical autohaemolysis.