Atypical spherocytosis, a disease of spleen as well as of red blood-cells.
作者信息
Garwicz S
出版信息
Lancet. 1975 Apr 26;1(7913):956-7. doi: 10.1016/s0140-6736(75)92012-7.
PMID:48127
Abstract
It is proposed that atypical spherocytosis is a result of severe spherocytosis combined with splenic dysfunction. The spleen exercises a "conditioning" effect on the red blood-cell but is insufficient in the "culling" and "pitting" functions. As a result, a large population of severely damaged erythrocytes is circulating in the peripheral blood giving rise to atypical autohaemolysis.
摘要
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