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Gas-chromatographic simultaneous analysis for glutethimide and an active hydroxylated metabolite in tissues, plasma, and urine.

作者信息

Hansen A R, Fischer L J

出版信息

Clin Chem. 1974 Feb;20(2):236-42.

PMID:4813002
Abstract
摘要

相似文献

1
Gas-chromatographic simultaneous analysis for glutethimide and an active hydroxylated metabolite in tissues, plasma, and urine.
Clin Chem. 1974 Feb;20(2):236-42.
2
Possible interference by a metabolite in gas chromatographic assays for glutethimide which employ certain non-selective liquid phases.在使用某些非选择性液相的格鲁米特气相色谱测定中，代谢物可能产生的干扰。
J Chromatogr. 1973 Dec 19;87(2):379-86. doi: 10.1016/s0021-9673(01)91738-8.
3
Determination of glutethimide (Doriden) and its metabolites in biologic specimens.生物样本中格鲁米特（多睡丹）及其代谢物的测定。
Clin Chem. 1968 Jul;14(7):595-609.
4
Letter: Specificity of analysis for glutethimide and its metabolites.
Clin Chem. 1974 Jul;20(7):919-20.
5
Concentration of glutethimide and associated compounds in huamn serum and cerebrospinal fluid after drug overdose.
Clin Chem. 1974 Feb;20(2):195-9.
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Glutethimide poisoning. A metabolite contributes to morbidity and mortality.
N Engl J Med. 1975 Jan 30;292(5):250-2. doi: 10.1056/NEJM197501302920507.
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Gas chromatographic determination of glutethimide in biological fluids.气相色谱法测定生物流体中的格鲁米特
J Chem Educ. 1974 Feb;51(2):133-5. doi: 10.1021/ed051p133.
8
Identification and activity of the hydroxy metabolite that accumulates in the plasma of humans intoxicated with glutethimide.
Drug Metab Dispos. 1974 Mar-Apr;2(2):151-8.
9
Metabolism of glutethimide in the human.
Res Commun Chem Pathol Pharmacol. 1975 Sep;12(1):25-41.
10
Rapid determination of glutethimide (Doriden) by gas-liquid chromatography.气液色谱法快速测定格鲁米特（导眠能）
Clin Chem. 1967 Jul;13(7):589-94.

引用本文的文献

1
Lack of correlation between plasma 4-hydroxyglutethimide and severity of coma in acute glutethimide poisoning. A case report and brief review of the literature.
Med Toxicol Adverse Drug Exp. 1987 Jul-Aug;2(4):309-16. doi: 10.1007/BF03259872.
2
Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.药理活性药物代谢物：治疗及毒性活性、人体血浆及尿液数据、肾衰竭时的蓄积情况
Clin Pharmacokinet. 1976 Nov-Dec;1(6):426-43. doi: 10.2165/00003088-197601060-00003.
3
[On the toxicology of carbromal. III. Role of active metabolites in humans acutely poisoned with carbromal-containing sedatives (author's transl)].[关于溴米那的毒理学。III. 活性代谢产物在含溴米那镇静剂急性中毒人类中的作用（作者译）]
Arch Toxicol. 1978 Jun 16;40(3):211-29. doi: 10.1007/BF00364653.