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Reconstitution of cytochrome P-450 and cytochrome P-450 reductase into phosphatidylcholine-phosphatidylethanolamine bilayers: characterization of structure and metabolic activity.

作者信息

Bösterling B, Stier A, Hildebrandt A G, Dawson J H, Trudell J R

出版信息

Mol Pharmacol. 1979 Jul;16(1):332-42.

PMID:481424
Abstract
摘要

相似文献

1
Reconstitution of cytochrome P-450 and cytochrome P-450 reductase into phosphatidylcholine-phosphatidylethanolamine bilayers: characterization of structure and metabolic activity.将细胞色素P-450和细胞色素P-450还原酶重组到磷脂酰胆碱-磷脂酰乙醇胺双层膜中：结构与代谢活性的表征
Mol Pharmacol. 1979 Jul;16(1):332-42.
2
Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine.含有细胞色素P-450、还原型三磷酸吡啶核苷酸-细胞色素P-450还原酶和磷脂酰胆碱的重组肝微粒体混合功能氧化酶系统的沉降及其他性质。
Mol Pharmacol. 1973 Jan;9(1):93-104.
3
Liver microsomal drug-metabolizing enzyme system: functional components and their properties.肝脏微粒体药物代谢酶系统：功能成分及其特性
Fed Proc. 1976 Nov;35(13):2460-3.
4
[Reconstitution of the monooxygenase system in a solution and in an immobilized phospholipid layer].[单加氧酶系统在溶液中和固定化磷脂层中的重构]
Biokhimiia. 1983 Dec;48(12):2002-8.
5
Role of phospholipid in the reconstituted liver microsomal mixed function oxidase system containing cytochrome P-450 and NADPH-cytochrome P-450 reductase.磷脂在含有细胞色素P - 450和NADPH - 细胞色素P - 450还原酶的重组肝微粒体混合功能氧化酶系统中的作用。
Drug Metab Dispos. 1973 Jan-Feb;1(1):156-61.
6
[Use of lipid exchange proteins for investigation of lipid dependence of rat liver cytochrome P-450].[利用脂质交换蛋白研究大鼠肝脏细胞色素P-450的脂质依赖性]
Biokhimiia. 1978 Mar;43(3):420-3.
7
Circadian changes of cytochrome P-450-dependent monooxygenase system in the rat liver.大鼠肝脏中细胞色素P-450依赖的单加氧酶系统的昼夜变化。
Pol J Pharmacol Pharm. 1992 Nov-Dec;44(6):655-61.
8
Dependence of microsomal methoxyflurane O-demethylation on cytochrome P-450 reductase and the stoichiometry of fluoride ion and formaldehyde release.
Anesth Analg. 1982 Jul;61(7):609-13.
9
Interaction between NADPH-cytochrome P-450 reductase and cytochrome P-450 in the membrane of phosphatidylcholine vesicles.烟酰胺腺嘌呤二核苷酸磷酸-细胞色素P-450还原酶与细胞色素P-450在磷脂酰胆碱囊泡膜中的相互作用。
Biochim Biophys Acta. 1979 Jan 19;550(2):341-56. doi: 10.1016/0005-2736(79)90220-7.
10
The NADPH-dependent cytochrome P-450 reduction in liver microsomes of rats of different ages with and without phenobarbital pretreatment.不同年龄、有无苯巴比妥预处理的大鼠肝脏微粒体中依赖烟酰胺腺嘌呤二核苷酸磷酸（NADPH）的细胞色素P - 450还原作用
Acta Biol Med Ger. 1975;34(8):1333-7.

引用本文的文献

1
Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity.细胞色素P450的组织与功能受内质网磷脂异质性调控。
Drug Metab Dispos. 2016 Dec;44(12):1859-1866. doi: 10.1124/dmd.115.068981. Epub 2016 May 27.
2
Organization of NADPH-cytochrome P450 reductase and CYP1A2 in the endoplasmic reticulum--microdomain localization affects monooxygenase function.NADPH-细胞色素 P450 还原酶和 CYP1A2 在内质网中的组织--微区定位影响单加氧酶功能。
Mol Pharmacol. 2011 Mar;79(3):549-57. doi: 10.1124/mol.110.068817. Epub 2010 Dec 14.
3
Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine.
在磷脂囊泡中重组的人细胞色素P-450对四氯化碳的还原代谢：与二油酰磷脂酰胆碱结合的三氯甲基自由基的质谱鉴定
Proc Natl Acad Sci U S A. 1982 Apr;79(8):2678-82. doi: 10.1073/pnas.79.8.2678.
4
Interaction of 7-n-alkoxycoumarins with cytochrome P-450(2) and their partitioning into liposomal membranes. Assessment of methods for determination of membrane partition coefficients.7-正烷氧基香豆素与细胞色素P-450(2)的相互作用及其在脂质体膜中的分配。膜分配系数测定方法的评估。
Biochem J. 1992 Jun 1;284 ( Pt 2)(Pt 2):483-90. doi: 10.1042/bj2840483.
5
Determination of the partition of the tetramisole derivative (+-)-5,6-dihydro-6-phenyl-2-n-propyl-imidazo[2,1-b]thiazole into liposomal membranes by fluorescence quenching of the membrane probe 8-(2-anthryl)-octanoic acid.通过膜探针8-(2-蒽基)-辛酸的荧光猝灭法测定四咪唑衍生物(±)-5,6-二氢-6-苯基-2-正丙基-咪唑并[2,1-b]噻唑在脂质体膜中的分配情况。
Eur Biophys J. 1992;21(1):47-56. doi: 10.1007/BF00195443.