尼日利亚的先天性心脏病。260例临床与尸检研究。
Congenital heart disease in Nigeria. Clinical and necropsy study of 260 cases.
作者信息
Antia A U
出版信息
Arch Dis Child. 1974 Jan;49(1):36-9. doi: 10.1136/adc.49.1.36.
Abstract
The present study of 260 combined necropsy and clinical cases of congenital heart defect has revealed that the various types of defects occur in the same proportions in Africans as in non-Africans. The frequency of associated noncardiac malformations, the cause of death, and sex distribution are similar to what has been described in non-Africans. Of the possible aetiological factors, there was evidence of a causal relation between maternal rubella infection and persistent ductus arteriosus. There was, however, no such evidence in respect of abnormal haemoglobins, maternal age, and birth rank.
摘要
本研究对260例先天性心脏缺陷的尸检与临床联合病例进行了分析，结果显示，非洲人与非非洲人各类心脏缺陷的发生比例相同。相关非心脏畸形的发生率、死因及性别分布与非非洲人情况相似。在可能的病因学因素中，有证据表明母体风疹感染与动脉导管未闭之间存在因果关系。然而，在异常血红蛋白、产妇年龄及生育顺序方面，并无此类证据。
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