胰凝乳蛋白酶催化作用的pH依赖性。附录：通过X射线衍射和平衡法研究底物与二聚体α-胰凝乳蛋白酶的结合 - Suppr

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pH dependence of chymotrypsin catalysis. Appendix: substrate binding to dimeric alpha-chymotrypsin studied by x-ray diffraction and the equilibrium method.

作者信息

Fersht A R, Renard M

出版信息

Biochemistry. 1974 Mar 26;13(7):1416-26. doi: 10.1021/bi00704a016.

DOI:10.1021/bi00704a016

PMID:4819756

Abstract

摘要

相似文献

pH dependence of chymotrypsin catalysis. Appendix: substrate binding to dimeric alpha-chymotrypsin studied by x-ray diffraction and the equilibrium method.胰凝乳蛋白酶催化作用的pH依赖性。附录：通过X射线衍射和平衡法研究底物与二聚体α-胰凝乳蛋白酶的结合

Biochemistry. 1974 Mar 26;13(7):1416-26. doi: 10.1021/bi00704a016.

-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?-胰凝乳蛋白酶：从X射线衍射中我们能了解到关于催化作用的哪些信息？

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Alpha-chymotrypsin: effects of bicyclic substrate geometry and hydrophobicity on reactivity.α-胰凝乳蛋白酶：双环底物几何形状和疏水性对反应活性的影响

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Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. A stereochemical interpretation.胰凝乳蛋白酶催化肽水解反应中的离去基团特异性。一种立体化学解释。

Biochemistry. 1973 May 22;12(11):2035-41. doi: 10.1021/bi00735a002.

Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.随着pH值变化，α-胰凝乳蛋白酶三级结构的变化：第4页，4.2 - 6.7

Biochemistry. 1973 Oct 9;12(21):4193-200. doi: 10.1021/bi00745a024.

The use of 13C n.m.r. and saturation transfer to detect tetrahedral intermediates in reactions catalysed by chymotrypsin and also in an amide inhibitor complex.利用13C核磁共振和饱和转移来检测胰凝乳蛋白酶催化反应以及酰胺抑制剂复合物中的四面体中间体。

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Analysis and elimination of protein perturbation in infrared difference spectra of acyl-chymotrypsin ester carbonyl groups by using 13C isotopic substitution.利用¹³C同位素取代分析并消除酰基 - 胰凝乳蛋白酶酯羰基红外差示光谱中的蛋白质干扰。

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