哌替啶不阻断震颤素的胆碱能效应。
Meperidine does not block the cholinergic effects of oxotremorine.
作者信息
Leander J D
出版信息
Pharmacol Biochem Behav. 1979 Jun;10(6):941-2. doi: 10.1016/0091-3057(79)90072-8.
PMID:482317
Abstract
Meperidine (20 and 40 mg/kg, IP) did not block the cholinergic effects (tremor, salivation, and tearing) produced by oxotremorine (0.4 mg/kg, SC) in rats, whereas atropine blocked these three effects (10 mg/kg, 2.5 mg/kg and 0.08 mg/kg, respectively.
摘要
哌替啶（20毫克/千克和40毫克/千克，腹腔注射）不能阻断氧化震颤素（0.4毫克/千克，皮下注射）对大鼠产生的胆碱能效应（震颤、流涎和流泪），而阿托品分别以10毫克/千克、2.5毫克/千克和0.08毫克/千克的剂量阻断了这三种效应。
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