焦碳酸二乙酯与丙酮酸激酶的反应。
The reaction of diethyl pyrocarbonate with pyruvate kinase.
作者信息
Dann L G, Britton H G
出版信息
Biochem J. 1974 Feb;137(2):405-7. doi: 10.1042/bj1370405.
Abstract
Diethyl pyrocarbonate inactivates muscle pyruvate kinase with the substitution of 3-4 histidine residues per subunit. Phosphoenolpyruvate, ATP and ADP to a lesser extent, and Mg(2+) and pyruvate to a small extent, protect against inactivation.
摘要
焦碳酸二乙酯使肌肉丙酮酸激酶失活，每个亚基有3 - 4个组氨酸残基被取代。磷酸烯醇式丙酮酸、ATP以及程度稍低的ADP，还有少量的Mg(2+)和丙酮酸可防止失活。
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