水奖励单次交替实验：异戊巴比妥钠对两种分别为高情绪性和低情绪性而选择性培育的大鼠品系的影响。

Single alternation with water reward:effects of sodium amobarbital on two strains of rats selectively bred for high and low emotionality.

作者信息

Guillamón A, Gray J A, Broadhurst P L

出版信息

Rev Esp Fisiol. 1979 Jun;35(2):169-74.

Abstract

The action of sodium amobarbital is studied during the patterning effect in rats selectively bred for low and high emotionality. The drug disrupts patterned running in the goal section of the alley in Maudsley non-reactive but not in Maudsley reactive rats for the last five trial-pairs. Sodium amobarbital also affects the behavior of these strains in a differential manner, in start and run sections, during the first trial-pair. The results show that a function-related physiological change has taken place in the Maudsley strains of rats.

摘要

对选择性培育的情绪低落和情绪高涨的大鼠进行模式化效应研究时，对异戊巴比妥钠的作用进行了研究。在最后五对试验中，该药物会干扰莫兹利非反应性大鼠在小巷目标区域的模式化奔跑，但不会干扰莫兹利反应性大鼠。在第一对试验中，异戊巴比妥钠在起始和奔跑区域也以不同方式影响这些品系的行为。结果表明，大鼠的莫兹利品系发生了与功能相关的生理变化。