苯巴比妥、3-甲基胆蒽、3,4-苯并芘和孕烯醇酮-16α-腈对微粒体血红素加氧酶和脾细胞色素P-450的影响 - Suppr

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The effect of phenobarbital, 3-methylcholanthrene, 3,4-benzpyrene, and pregnenolone-16 alpha-carbonitrile on microsomal heme oxygenase and splenic cytochrome P-450.

作者信息

Schacter B A, Mason J I

出版信息

Arch Biochem Biophys. 1974 Jan;160(1):274-8. doi: 10.1016/s0003-9861(74)80034-2.

DOI:10.1016/s0003-9861(74)80034-2

PMID:4828525

Abstract

摘要

相似文献

The effect of phenobarbital, 3-methylcholanthrene, 3,4-benzpyrene, and pregnenolone-16 alpha-carbonitrile on microsomal heme oxygenase and splenic cytochrome P-450.苯巴比妥、3-甲基胆蒽、3,4-苯并芘和孕烯醇酮-16α-腈对微粒体血红素加氧酶和脾细胞色素P-450的影响

Arch Biochem Biophys. 1974 Jan;160(1):274-8. doi: 10.1016/s0003-9861(74)80034-2.

Induction of rat hepatic microsomal cytochrome P-450 by 2,3',4,4',5,5'-hexachlorobiphenyl.2,3',4,4',5,5'-六氯联苯对大鼠肝微粒体细胞色素P-450的诱导作用

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The effect of phenobarbital, 3-methylcholanthrene, and pregnenolone-16 alpha-carbonitrile on the N-demethylation and O-de-ethylation of [6-H3]ethylmorphine.苯巴比妥、3-甲基胆蒽及孕烯醇酮-16α-腈对[6-H³]乙基吗啡N-去甲基化和O-去乙基化的影响。

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Effect of a catatoxic steroid pregnenolone-16alpha-carbonitrile, on rat liver microsomal subfractions.

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Effects of clophen A50, 3-methylcholanthrene, pregnenolone-16 alpha-carbonitrile, and phenobarbital on the hepatic microsomal cytochrome P-450-dependent monooxygenase system in rainbow trout, Salmo gairdneri, of different age and sex.氯芬A50、3-甲基胆蒽、孕烯醇酮-16α-腈和苯巴比妥对不同年龄和性别的虹鳟（Salmo gairdneri）肝脏微粒体细胞色素P-450依赖性单加氧酶系统的影响。

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Microsomal NADPH-dependent lipid peroxidation does not require the presence of intact cytochrome P450.微粒体NADPH依赖性脂质过氧化作用并不需要完整的细胞色素P450的存在。

Biochem Biophys Res Commun. 1980 Aug 29;95(4):1510-6. doi: 10.1016/s0006-291x(80)80068-4.

Pregnenolone-16alpha-carbonitrile-inducible cytochrome P450 in rat liver.孕烯醇酮-16α-腈诱导的大鼠肝脏细胞色素P450

Res Commun Chem Pathol Pharmacol. 1976 Nov;15(3):553-62.

Aryl and aniline hydroxylases in rat nuclear membranes after pretreatment with pregnenolone 16alpha-carbonitrile, phenobarbital and methylcholanthrene.经孕烯醇酮16α-腈、苯巴比妥和甲基胆蒽预处理后大鼠核膜中的芳基和苯胺羟化酶

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Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretreatment.苯巴比妥和3,4-苯并芘处理大鼠对去甲替林和去甲基丙咪嗪微粒体结合及羟基化的影响：苯巴比妥预处理后细胞色素P-450-配体相互作用发生质性变化的证据。

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Drug Metab Dispos. 1973 Jan-Feb;1(1):199-210.

引用本文的文献

Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity.钴对肝脏血红素加氧酶的诱导作用；有证据表明细胞色素P-450对此酶活性并非必不可少。

Proc Natl Acad Sci U S A. 1974 Nov;71(11):4293-7. doi: 10.1073/pnas.71.11.4293.

Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.肝脏血红素代谢的调节。药物和金属诱导血红素加氧酶的不同机制。

Biochem J. 1988 Feb 15;250(1):189-96. doi: 10.1042/bj2500189.

Effects of the environmental pollutants on heme oxygenase activity and cytochrome P-450 content in fish.

Bull Environ Contam Toxicol. 1990 Feb;44(2):189-96. doi: 10.1007/BF01700135.

Induction of 16alpha-hydroxylase in cultured human lymphocytes.培养的人淋巴细胞中16α-羟化酶的诱导

Biochem Genet. 1975 Aug;13(7-8):501-9. doi: 10.1007/BF00485791.

Study of the developmental pattern of heme catabolism in liver and the effects of cobalt on cytochrome P-450 and the rate of heme oxidation during the neonatal period.新生儿期肝脏血红素分解代谢发育模式及钴对细胞色素P-450和血红素氧化速率影响的研究。

J Exp Med. 1975 Jun 1;141(6):1400-10. doi: 10.1084/jem.141.6.1400.

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