Muller K J, Scott S A
Science. 1979 Oct 5;206(4414):87-9. doi: 10.1126/science.482931.
The unique target neuron of a severed axon in the leech was selectively eliminated by intracellular injection of protease. In the absence of the target, the severed axon regenerated normally along its original pathway to the usual site of synapse, where it stopped growing without forming alternative connections.
通过细胞内注射蛋白酶，选择性地消除了水蛭中被切断轴突的独特靶神经元。在没有靶标的情况下，被切断的轴突沿着其原始路径正常再生至通常的突触部位，在那里它停止生长，没有形成替代连接。
