Grondalen T, Grondalen J
Acta Vet Scand. 1974;15(1):53-60. doi: 10.1186/BF03547493.
The effect of overloading on the distal epiphyseal plate of the ulna is described. The right forelegs of 6 pigs were fixed such that the pigs were forced to walk on 3 legs during 2 periods, the first of 12 days duration at about 50 kg live weight, and the second of 7 days at about 100 kg live weight. Osteochondrosis developed to a more marked degree in the left than in the right epiphyseal plate of the ulna, but this did not lead to reduced lengthwise growth of the bones to any great extent. The overloading led to reversible changes in the distal epiphyseal plate of the ulna. It is conceivable that this was due to disturbances in the metaphyseal blood flow. It is also conceivable that the overloading was neither great enough nor of sufficient duration to affect the epiphyseal blood flow with consequential irreversible damage to, and premature closure of, the epiphyseal plate.
描述了超负荷对尺骨远端骨骺板的影响。6头猪的右前肢被固定，使猪在两个阶段被迫用三条腿行走，第一个阶段持续12天，体重约50公斤，第二个阶段持续7天，体重约100公斤。尺骨左侧骨骺板的骨软骨病发展程度比右侧更明显，但这并未导致骨骼纵向生长有任何显著减少。超负荷导致尺骨远端骨骺板出现可逆性变化。可以想象，这是由于干骺端血流紊乱所致。也可以想象，超负荷程度既不够大，持续时间也不够长，不足以影响骨骺血流，从而对骨骺板造成不可逆损伤并使其过早闭合。
