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Abdominal aortic coarctation and segmental hypoplasia.腹主动脉缩窄和节段性发育不全。
Surgery. 1979 Oct;86(4):519-29.
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腹主动脉缩窄和节段性发育不全。

Abdominal aortic coarctation and segmental hypoplasia.

作者信息

Graham L M, Zelenock G B, Erlandson E E, Coran A G, Lindenauer S M, Stanley J C

出版信息

Surgery. 1979 Oct;86(4):519-29.

PMID:483161
Abstract

Functionally significant, nonatherosclerotic, noninflammatory, concentric and tubular stenoses of the abdominal aorta, 4 to 16 cm in length, were encountered in five male and five female patients 11 to 49 years old. Seven patients were younger than 19 years of age. Aortic branch stenoses were common, affecting splanchnic vessels in seven patients and renal arteries in eight patients. The pathogenesis of the aortic constrictive lesions remains unknown, but it may be related to developmental error or aortic growth arrest. Existence of multiple renal arteries in 70% of these patients lends support to the developmental hypothesis. Intimal fibroplasia characterized stenotic aortic tissue. Severe hypertension was common, with the mean preoperative arterial pressure being 200/119 mm Hg. Thoracoabdominal bypass was undertaken in eight patients, being combined with renovascular reconstruction on five occasions. Two patients underwent patch graft aortoplasty with bilateral renal revascularization. Therapeutic results were classified as excellent six times and as good four times. Single-stage arterial reconstructions are the preferred method of treatment for abdominal aortic coarctation or segmental hypoplasia with associated aortic branch disease.

摘要

在5名年龄为11至49岁的男性患者和5名女性患者中,发现腹主动脉存在功能显著、非动脉粥样硬化、非炎性、同心性和管状狭窄,长度为4至16厘米。7名患者年龄小于19岁。主动脉分支狭窄很常见,7名患者的内脏血管和8名患者的肾动脉受到影响。主动脉狭窄性病变的发病机制尚不清楚,但可能与发育异常或主动脉生长停滞有关。这些患者中有70%存在多条肾动脉,这支持了发育假说。狭窄的主动脉组织表现为内膜纤维增生。严重高血压很常见,术前平均动脉压为200/119毫米汞柱。8名患者接受了胸腹旁路手术,其中5次与肾血管重建联合进行。两名患者接受了补片移植主动脉成形术并双侧肾血管重建。治疗结果6次评为优秀,4次评为良好。对于腹主动脉缩窄或节段性发育不全合并主动脉分支疾病,一期动脉重建是首选的治疗方法。