Zizkovský V, Kordac V, Stĕpán J, El'gort D N
Acta Hepatogastroenterol (Stuttg). 1975 Apr;22(2):92-7.
The presence of alpha-1-fetoprotein, the heat stable alkaline phosphatase and Australia antigen was examined in 103 patients with porphyria cutanea tarda, 300 patients with cirrhosis and 18 patients with primary liver carcinoma. The heat stable alkaline phosphatase was determined in 46 percent of patients with porphyria cutanea tarda and in 61 percent of patients with primary liver carcinoma. Alpha-1-fetoprotein was detected in 61 percent of patients with primary liver carcinoma and in 2 patients with porphyria cutanea tarda in whom primary liver carcinoma was proved later. The simultaneous occurrence of alpha-1-fetoprotein and the heat stable alkaline phosphatase was found in 50 percent of cases with primary liver carcinoma. Neither the patients with porphyria cutanea tarda nor the patients with cirrhosis were Australia-antigen positive. Australia-antigen could be detected only in one patient with alpha-1-fetoprotein positive-carcinoma of the liver.
对103例迟发性皮肤卟啉病患者、300例肝硬化患者和18例原发性肝癌患者检测了甲胎蛋白、热稳定碱性磷酸酶和澳大利亚抗原。46%的迟发性皮肤卟啉病患者和61%的原发性肝癌患者检测到热稳定碱性磷酸酶。61%的原发性肝癌患者以及2例后来被证实患有原发性肝癌的迟发性皮肤卟啉病患者检测到甲胎蛋白。50%的原发性肝癌病例同时出现甲胎蛋白和热稳定碱性磷酸酶。迟发性皮肤卟啉病患者和肝硬化患者均无澳大利亚抗原阳性。仅在1例甲胎蛋白阳性的肝癌患者中检测到澳大利亚抗原。
