Doolittle R F, Takagi T, Cottrell B A
Science. 1974 Jul 26;185(4148):368-70. doi: 10.1126/science.185.4148.368.
Human platelet fibrinogen has been shown to be indistinguishable from plasma fibrinogen by a variety of criteria, including subunit composition and cross-linking characteristics as judged by sodium dodecyl sulfate-gel electro phoresis, quantitative amino terminal analysis of fibrin, and the amino acid compositions of fibrinopeptides released from platelet and plasma fibrinogens is products of the same gene or genes.
通过多种标准已表明,人血小板纤维蛋白原与血浆纤维蛋白原无法区分,这些标准包括通过十二烷基硫酸钠 - 凝胶电泳判断的亚基组成和交联特性、纤维蛋白的定量氨基末端分析,以及从血小板和血浆纤维蛋白原释放的纤维蛋白肽的氨基酸组成,表明它们是同一基因或多个基因的产物。