Storch W, Voigt H
Z Gesamte Inn Med. 1979 May 15;34(10):124-6.
10 of 14 patients with obliterating endangiitis and 2 of 17 patients with obliterating arteriosclerosis had in the serum immunoflorescence-optically provable low titre antibodies against different constituents of smooth musculature (once cross-reacting with transverse and cross striation of the myocardium). Further antibodiies against brush border of proximal renal tubuli, parietal cells, cardiac sarcolemma, cytoplasm of the liver and distal renal tubuli were found. Antibodies against nuclear material, skeletal musculature, further typical antibodies against mitochondria, ribosomes and membranes of the endoplasmatic reticulum as well as so-called pemphigus and pemphigoid antibodies could not be proved. The proof of low titre antibodies against constituents of smooth musculature is in this case regarded as an unspecific marker of an (often) viral inflammation.
14例闭塞性血管内膜炎患者中有10例,17例闭塞性动脉硬化患者中有2例,血清免疫荧光检查可证实其血清中存在针对平滑肌不同成分的低滴度抗体(有一次与心肌的横纹和交叉横纹发生交叉反应)。此外,还发现了针对近端肾小管刷状缘、壁细胞、心肌肌膜、肝细胞质和远端肾小管的抗体。未检测到针对核物质、骨骼肌、线粒体、核糖体和内质网的典型抗体以及所谓的天疱疮和类天疱疮抗体。在这种情况下,针对平滑肌成分的低滴度抗体的检测被视为(通常)病毒感染炎症的非特异性标志物。