Lamberti G
Z Geburtshilfe Perinatol. 1979 Jun;183(3):175-88.
Cervical ripening before labors is not an exclusively passive process by uterine contractions. On the contrary, we can find a lot of highly active processes in the cervical connective tissue with changes in metabolism of the cells leading to changes in the ground substance and the organisation and structure of collagenous fibres. We do not as yet know the trigger mechanisms of the prepartum cervical rpiening. Probably prostaglandins and relaxin are such triggering substances. At present, our new understanding of this active cervical process does not help the obstetrician. There is no laboratory test up to now. Cervical ripeness can only be examined on the basis of clinical criteria: length, consistency, position, and dilatation of the cervix uteri and station of the fetal head. The most usual score of cervical ripeness is Bishop's Pelvic-score. A high scoring excludes failures of induction of labor. But the rate of wrong prognosis, concerning efficiency of induction and time of labor is relatively high in cases with low rating of cervical ripeness. A more differentiated scoring of some of the criteria and some weighing of these seems to lead to better prognosis. On the other hand, recent clinical experiences with prostaglandins lead us to expect that we will be able to induce cervical ripeness.
分娩前的宫颈成熟并非仅仅是子宫收缩的被动过程。相反,我们可以在宫颈结缔组织中发现许多高度活跃的过程,这些过程伴随着细胞代谢的变化,进而导致细胞外基质以及胶原纤维的组织和结构发生改变。我们目前尚不清楚产前宫颈成熟的触发机制。前列腺素和松弛素可能就是这类触发物质。目前,我们对宫颈这一活跃过程的新认识对产科医生并无帮助。到目前为止还没有实验室检测方法。宫颈成熟度只能依据临床标准进行检查:宫颈的长度、质地、位置、扩张程度以及胎头的位置。最常用的宫颈成熟度评分是 Bishop 骨盆评分。高分可排除引产失败的情况。但在宫颈成熟度评分较低的病例中,关于引产效率和分娩时间的预后错误率相对较高。对某些标准进行更细致的评分以及对这些标准进行一定的权衡似乎能带来更好的预后。另一方面,近期使用前列腺素的临床经验让我们期待能够诱导宫颈成熟。