Price L A, Hill B T, Calvert A H, Shaw H J, Hughes K B
Br Med J. 1975 Jul 5;3(5974):10-1. doi: 10.1136/bmj.3.5974.10.
A multiple drug regimen was given to 36 patients with advanced carcinomas of the head and neck. In 19 of the 24 patients who were assessable the tumour regressed more than 50%; in one it regressed by 25%; and in four it did not respond at all. Multiple drug chemotherapy should be given much earlier in the course of these cancers, preferably as an adjuvant to surgery or radiotherapy.
对36例晚期头颈癌患者采用了多药联合治疗方案。在可评估的24例患者中,19例肿瘤缩小超过50%;1例缩小25%;4例完全无反应。对于这些癌症,多药化疗应在病程中更早给予,最好作为手术或放疗的辅助治疗。