Oliveira M C, Pinto e Silva P, Orsi A M, Mello Dias S
Acta Anat (Basel). 1979;104(3):319-22. doi: 10.1159/000145077.
The ductus arteriosus was studied in 138 dogs (80 female and 58 male) aged from 6 h to 21 days. This experiment led us to conclude that the anatomical closure of the d. arteriosus starts within 96 h and is obliterated after 6 days in 100% of the animals studied. We have also evidenced that the closure starts in the medial part of the d. arteriosus and progresses to the pulmonary artery and aorta.
对138只年龄从6小时至21天的犬（80只雌性和58只雄性）的动脉导管进行了研究。该实验使我们得出结论，动脉导管的解剖学闭合在96小时内开始，并且在研究的100%的动物中，6天后完全闭塞。我们还证明，闭合始于动脉导管的内侧部分，并向肺动脉和主动脉发展。
