Dobbs G H, Lin Y, DeVries A L
Science. 1974 Aug 30;185(4153):793-4. doi: 10.1126/science.185.4153.793.
Urine formation in antarctic bony fish does not involve glomerular filtration. Evidence for aglomerularism came from both direct observation of kidney serial sections by light microscopy and the low concentrations of inulin labeled with carbon-14 that were excreted into the urine when this renal clearance tracer was injected into the bloodstream via a cannula implanted in the caudal vein. Aglomerularism most likely prevents urinary loss of glycoproteins with biological antifreeze properties.
南极硬骨鱼的尿液形成不涉及肾小球滤过。无肾小球现象的证据来自于通过光学显微镜对肾脏连续切片的直接观察,以及当通过植入尾静脉的套管将这种肾清除示踪剂注入血液时,排泄到尿液中的低浓度碳 - 14标记菊粉。无肾小球现象很可能防止了具有生物防冻特性的糖蛋白随尿液流失。