Thomsen J, Vesterhauge S
Adv Otorhinolaryngol. 1979;25:49-53. doi: 10.1159/000402916.
From the literature it is apparent that the glycerol test is being used frequently to evaluate Meniere patients, with regard to the choice of treatment, and in particular to find those who are suitable for surgery with different decompressive procedures. In our previous investigations on such patients we found that they often are extremely good placebo responders and it was natural to evaluate how important such psychological factors would be for the outcome of the glycerol test. In a group of patients with typical objective and subjective symptoms of Meniere's disease, the glycerol test was applied twice to each patient. In one of the tests, the patient was told that we would expect hearing to improve. In the other test, where the actual amount of glycerol was the same, we had the solution prepared with a different taste, and the patient was informed that we now would expect the hearing to deteriorate. The sequence of the two tests was randomly chosen for each patient. Most frequently the patient would follow our instructions, i.e. obtained a poorer hearing threshold when instructed to, and vice versa. The results are discussed with a special view to the risk of selection of suggestion-sensitive patients by this test.
从文献中可以明显看出，甘油试验经常被用于评估梅尼埃病患者，以辅助治疗方案的选择，特别是用于找出适合不同减压手术的患者。在我们之前对这类患者的研究中，我们发现他们往往是非常好的安慰剂反应者，因此很自然地要评估这种心理因素对甘油试验结果的影响程度。在一组具有典型梅尼埃病客观和主观症状的患者中，对每位患者进行了两次甘油试验。在其中一次试验中，告知患者我们预期听力会改善。在另一次试验中，甘油的实际用量相同，但我们将溶液调配成不同的味道，并告知患者我们预期听力会恶化。每次试验的顺序是为每位患者随机选择的。大多数情况下，患者会听从我们的指示，即在被告知听力会恶化时听力阈值变差，反之亦然。我们将结合该试验筛选出对暗示敏感患者的风险这一特殊视角来讨论这些结果。
