萘磺酸丙氧芬在治疗海洛因和美沙酮成瘾中的应用。
The use of propoxyphene napsylate in the treatment of heroin and methadone addiction.
作者信息
Inaba D S, Gay G R, Whitehead C A, Newmeyer J A, Bergin D
出版信息
West J Med. 1974 Aug;121(2):106-11.
The use of methadone in the treatment of heroin addiction continues to be controversial. Propoxyphene napsylate (Darvon N(R)) is a possible alternative and a pilot study was conducted to test its acceptability, safety and clinical efficacy in treating long term, "multi-relapse" heroin addicts. Findings indicate that propoxyphene napsylate suppresses many of the symptoms associated with opioid withdrawal phenomena. It should be viewed as a very promising therapeutic tool to be used in conjunction with psychological counseling and socio-vocational rehabilitation in detoxification and maintenance therapy for heroin or methadone addiction.
美沙酮用于治疗海洛因成瘾一直存在争议。萘磺酸丙氧芬（达尔丰N(R)）是一种可能的替代药物，为此开展了一项试点研究，以测试其在治疗长期“多次复吸”海洛因成瘾者方面的可接受性、安全性和临床疗效。研究结果表明，萘磺酸丙氧芬可抑制许多与阿片类戒断现象相关的症状。在海洛因或美沙酮成瘾的解毒和维持治疗中，它应被视为一种非常有前景的治疗工具，可与心理咨询和社会职业康复相结合使用。
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