Bourdais A, Le Bris H, Barnaud P, Bouffard A, Jaud V, Richard A, Vincent M, Courbil L J
Anesth Analg (Paris). 1979 Mar-Apr;36(3-4):133-8.
Two varieties of conditions of shock may be isolated during necrotic amoebic colitis (13 cases). Eight patients present a simple hypovolemic shock secondary to wastage by diarrhea and perilesional oedema with globular, protein, alcaline and potassic deficiency. Its prognosis is relatively good, after vascular infilling and corrections of metabolic disorders. Five other patients present real toxi-infectious shock resulting from widespread tissue necrosis with auto-intoxication associated with septicemic complications. Its prognosis is frankly bad. The treatment is far more difficult. The use of cardiovascular analeptics, such as dopamine, after an infilling failure, is not always sufficient to re-establish the situation. The exeresis of necrotic tissues is an indispensable condition to remove the cause of the shock before septicaemic generalisation.
在坏死性阿米巴结肠炎（13例）中可区分出两种休克状态。8例患者出现单纯性低血容量性休克，继发于腹泻和病灶周围水肿导致的体液丢失，伴有球蛋白、蛋白质、碱性物质和钾缺乏。经血管充盈和代谢紊乱纠正后，其预后相对较好。另外5例患者出现真正的中毒性感染性休克，是由广泛的组织坏死伴自身中毒及败血症并发症引起的。其预后明显不良，治疗困难得多。在补液失败后使用心血管兴奋剂，如多巴胺，并不总能恢复病情。切除坏死组织是在败血症播散前消除休克病因的必要条件。
