Meador K H, Sharon Z, Lewis E J
Ann Intern Med. 1979 Oct;91(4):565-7. doi: 10.7326/0003-4819-91-4-565.
Two drug addicts who practiced subcutaneous injection of crushed tripelennamine and pentazocine tablets, a practice known as "skin-popping," developed nephrotic syndrome and demonstrated amyloidosis on renal biopsy. These patients had chronic inflammation of the skin in the form of abscesses and ulcerations. Although both patients were long-standing drug abusers, they had practiced intradermal drug administration for only 3 years. The occurrence of amyloidosis in these patients appears to relate to their particular drug habir and must be considered in the differential diagnosis of proteinuria in this patient population.
两名吸毒者通过皮下注射碾碎的曲吡那敏和喷他佐辛片剂（这种做法被称为“皮肤注射”），患上了肾病综合征，并且肾活检显示有淀粉样变性。这些患者有以脓肿和溃疡形式存在的慢性皮肤炎症。尽管两名患者都是长期吸毒者，但他们进行皮内给药仅3年。这些患者中淀粉样变性的发生似乎与他们特定的吸毒习惯有关，在对该患者群体蛋白尿进行鉴别诊断时必须予以考虑。
