Medved A, Maxwell I
Can Med Assoc J. 1974 Aug 3;111(3):245 passim.
Cyclophosphamide, given in widely spaced doses, was used in the treatment of a patient with pemphigus vulgaris and a patient with bullous pemphigoid. To our knowledge, this form of therapy has not previously been reported in these two diseases. The distinct advantages of the larger intermittent dose method of cyclophosphamide therapy over the more conventional daily dose regimen are discussed.
环磷酰胺以间隔时间较长的剂量给药，用于治疗一名寻常型天疱疮患者和一名大疱性类天疱疮患者。据我们所知，这种治疗方式此前尚未在这两种疾病中报道过。文中讨论了环磷酰胺治疗采用较大间隔剂量方法相较于更传统的每日剂量方案所具有的明显优势。
