2,2'-脱水-1-(β-D-阿拉伯呋喃糖基)胞嘧啶盐酸盐（NSC-145668）某些衍生物的合成及生物学检测 - Suppr

Synthesis and biologic examination of some derivatives of 2,2'-anhydro-1-(beta-d-arabinofuranosyl)cytosine hydrochloride (NSC-145668).

作者信息

Moffatt J G, Hamamura E K, Russell A F, Prystasz M, Verheyden J P, Yamaguchi K, Uchida N, Sato K, Nishiyama S, Shiratori O, Katagiri K

出版信息

Cancer Chemother Rep. 1974 Jul-Aug;58(4):451-69.

PMID:4854565

Abstract

摘要

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Synthesis and biologic examination of some derivatives of 2,2'-anhydro-1-(beta-d-arabinofuranosyl)cytosine hydrochloride (NSC-145668).2,2'-脱水-1-(β-D-阿拉伯呋喃糖基)胞嘧啶盐酸盐（NSC-145668）某些衍生物的合成及生物学检测

Cancer Chemother Rep. 1974 Jul-Aug;58(4):451-69.

Pyrimidine nucleosides. 6. Syntheses and anticancer activities of N4-substituted 2,2'-anhydronucleosides.嘧啶核苷。6. N4-取代的2,2'-脱水核苷的合成及抗癌活性。

J Med Chem. 1974 Oct;17(10):1076-8. doi: 10.1021/jm00256a010.

Reactions of 2-acyloxyisobutyryl halides with nucleosides. 6. Synthesis and biological evaluation of some 3'-acyl derivatives of 2,2'-anhydro-1-(beta-D-arabinofuranosyl)cytosine hydrochloride.2-酰氧基异丁酰卤与核苷的反应。6. 2,2'-脱水-1-(β-D-阿拉伯呋喃糖基)胞嘧啶盐酸盐的一些3'-酰基衍生物的合成及生物学评价

J Med Chem. 1976 May;19(5):654-62. doi: 10.1021/jm00227a016.

A comparative study of the antitumor and antiviral activity of 1-beta-D-arabinofuranosyl-5-fluorocytosine (FCA) and 1-beta-D-arabinofuranosylcytosine (CA).1-β-D-阿拉伯呋喃糖基-5-氟胞嘧啶（FCA）与1-β-D-阿拉伯呋喃糖基胞嘧啶（CA）的抗肿瘤和抗病毒活性的比较研究。

Proc Soc Exp Biol Med. 1969 Apr;130(4):1080-6. doi: 10.3181/00379727-130-33724.

Reactions of 2-acyloxyisobutyryl halides with nucleosides. 7. Synthesis and biological evaluation of some 2,2'-anhydro-1(3',5'-di-O-acyl-beta-D-arabinofuranosyl)cytosine hydrochlorides.2-酰氧基异丁酰卤与核苷的反应。7. 某些2,2'-脱水-1(3',5'-二-O-酰基-β-D-阿拉伯呋喃糖基)胞嘧啶盐酸盐的合成及生物学评价。

J Med Chem. 1976 May;19(5):663-7. doi: 10.1021/jm00227a017.

Studies on biologically active nucleosides and nucleotides. 5. Synthesis and antitumor activity of some 2,2'-anhydro-1-(3',5'-di-O-acyl-beta-D-arabinofuranosyl)cytosine salts and 2,2'-anhydro-1-(3'-O-acyl-beta-D-arabinofuranoxyl)cytosine 5'-phosphates.

J Med Chem. 1979 Jun;22(6):639-46. doi: 10.1021/jm00192a007.

Nucleic acids. 12. Synthesis of the L enantiomer of 1- -arabinofuranosylcytosine and of O 2 ,O 2' -anhydro-1- -D-arabinofuranosylcytosine.

J Med Chem. 1971 Sep;14(9):882-3. doi: 10.1021/jm00291a027.

Reactions of 2-acyloxyisobutyryl halides with nucleosides. Synthesis and biological evaluation of some 3"-acyl and 3',5'-diacyl derivatives of 1-beta-D-arabinofuranosylcytosine.2-酰氧基异丁酰卤与核苷的反应。1-β-D-阿拉伯呋喃糖基胞嘧啶的一些3''-酰基和3',5'-二酰基衍生物的合成及生物学评价。

J Med Chem. 1976 May;19(5):667-74. doi: 10.1021/jm00227a018.

Pyrimidine nucleosides. 5. Syntheses of carcinostatic halogenocyclonucleosides.嘧啶核苷。5. 抗癌卤代环核苷的合成。

J Med Chem. 1972 Dec;15(12):1218-21. doi: 10.1021/jm00282a004.

Nucleic acids. 11. Synthesis of 5'-esters of 1-beta-D-arabinofuranosylcytosine possessing antileukemic and immunosuppressive activity.核酸。11. 具有抗白血病和免疫抑制活性的1-β-D-阿拉伯呋喃糖基胞嘧啶5'-酯的合成。

J Med Chem. 1971 Dec;14(12):1159-62. doi: 10.1021/jm00294a004.

引用本文的文献

Comparative study of the antiviral activity of acyl derivatives of 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine and other nucleosides against encephalitis in mice.2,2'-脱水-1-β-D-阿拉伯呋喃糖基胞嘧啶的酰基衍生物及其他核苷对小鼠脑炎抗病毒活性的比较研究

Antimicrob Agents Chemother. 1977 Feb;11(2):198-201. doi: 10.1128/AAC.11.2.198.

Antiviral activities of acyl derivatives of 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosylcytosine in cell culture.2,2'-脱水-1-β-D-阿拉伯呋喃糖基胞嘧啶和1-β-D-阿拉伯呋喃糖基胞嘧啶的酰基衍生物在细胞培养中的抗病毒活性。

Antimicrob Agents Chemother. 1977 Feb;11(2):191-7. doi: 10.1128/AAC.11.2.191.

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Synthesis and biologic examination of some derivatives of 2,2'-anhydro-1-(beta-d-arabinofuranosyl)cytosine hydrochloride (NSC-145668).

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