蛋白尿后恢复青霉胺治疗。
Resumption of treatment with penicillamine after proteinuria.
作者信息
Hill H, Hill A, Davison A M
出版信息
Ann Rheum Dis. 1979 Jun;38(3):229-31. doi: 10.1136/ard.38.3.229.
Abstract
Penicillamine has been successfully reintroduced and continued for a minimum of 13 months in 5 patients who developed proteinuria during the first course of the drug. The daily maintenance dose during the second course was 150--250 mg taken midway between 2 meals. Proteinuria did not recur; no significant excretion of fibrin degradation products occurred; complement, urea, creatinine, and serum albumin remained within normal limits. Urine microscopy showed no abnormality.
摘要
青霉胺已成功地再次应用于5例在该药第一个疗程中出现蛋白尿的患者，并持续使用了至少13个月。第二个疗程的每日维持剂量为150 - 250毫克，在两餐之间服用。蛋白尿未复发；未出现纤维蛋白降解产物的显著排泄；补体、尿素、肌酐和血清白蛋白仍在正常范围内。尿液显微镜检查未显示异常。
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