Hurtado del Rio D, Holden Barker A M, Pezzotti M A, Gutiérrez Bosque R, Archundia A, Pérez Mejia J, Carrillo H
Arch Inst Cardiol Mex. 1979 Jul-Aug;49(4):662-72.
Sixteen newborn babies with severe respiratory distress and patent ductus arteriosus with congestive heart failure are presented. Fifteen of them were premature and one at full term. Management consisted of the accepted medical and ventilatory aids such as digitalis, diuretics, ventilators, etc. Thirteen cases were given indomethacin with clinical closure in five of them (38%). Ten cases underwent surgical closure with 30% mortality. It is recommended that these patients be given indomethacin inicially; if there is no response in 36 hours surgical closure of the duct should be performed prior to progressive deterioration and eventual death.
本文报告了16例患有严重呼吸窘迫和动脉导管未闭并伴有充血性心力衰竭的新生儿。其中15例为早产儿，1例为足月儿。治疗措施包括采用公认的药物和通气辅助手段，如使用洋地黄、利尿剂、呼吸机等。13例患儿使用了吲哚美辛，其中5例（38%）实现了临床治愈。10例患儿接受了手术结扎，死亡率为30%。建议首先给予这些患儿吲哚美辛治疗；如果36小时内无反应，则应在病情进一步恶化和最终死亡之前进行动脉导管手术结扎。
