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绒毛尿囊膜麻疹：一种新型进一步减毒麻疹疫苗的研发与临床评估

Chorioallantoic membrane measles: development and clinical evaluation of a new further attenuated measles vaccine.

作者信息

Cerini C P, Arguedas J, Hernandez G, Frickey P, Douglas A V

出版信息

Appl Microbiol. 1974 Apr;27(4):763-6. doi: 10.1128/am.27.4.763-766.1974.

DOI:10.1128/am.27.4.763-766.1974
PMID:4856949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC380131/
Abstract

A new, further attenuated measles vaccine, developed by propagation of Edmonston B measles virus in the chorioallantoic membrane in ovo, has been clinically evaluated in children and found to compare favorably with a commercially available product. The vaccine is prepared in chick embryo tissue culture and appears to possess noteworthy stability at 4 C.

摘要

一种新的、进一步减毒的麻疹疫苗，是通过在鸡胚尿囊膜中传代Edmonston B麻疹病毒研制而成，已在儿童中进行了临床评估，结果发现其与市售产品相比具有优势。该疫苗在鸡胚组织培养中制备，在4℃下似乎具有显著的稳定性。

相似文献

1
Chorioallantoic membrane measles: development and clinical evaluation of a new further attenuated measles vaccine.绒毛尿囊膜麻疹：一种新型进一步减毒麻疹疫苗的研发与临床评估
Appl Microbiol. 1974 Apr;27(4):763-6. doi: 10.1128/am.27.4.763-766.1974.
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Biken J. 1971 Sep;14(3):253-8.
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Studies on further attenuated live measles vaccine. I. Adaptation of measles virus to the chorioallantoic membrane of chick embryo and clinical tests on the strain.进一步减毒活麻疹疫苗的研究。I. 麻疹病毒对鸡胚绒毛尿囊膜的适应及该毒株的临床试验。
Biken J. 1970 Jun;13(2):111-6.
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OBSERVATIONS ON THE FURTHER ATTENUATION OF MEASLES VIRUS AND ON LIVE VACCINES PREPARED FROM HIGHLY ATTENUATED LINES OF VIRUS.关于麻疹病毒的进一步减毒及由高度减毒株制备的活疫苗的观察
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Experimental studies on attenuated measles virus.
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Rev Roum Virol (1972). 1973;10(1):8-17.
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Combined trivalent and bivalent measles, mumps and rubella virus vaccination. A controlled trial.三价与二价麻疹、腮腺炎和风疹病毒联合疫苗接种。一项对照试验。
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Immune response to Edmonston-Zagreb measles virus strain in monovalent and combined MMR vaccine.对单价及联合麻腮风疫苗中埃登斯顿- Zagreb麻疹病毒株的免疫反应。
Dev Biol Stand. 1986;65:95-100.

本文引用的文献

1
AN ACCELERATED STORAGE TEST FOR PREDICTING THE STABILITY OF SUSPENSIONS OF MEASLES VIRUS DRIED BY SUBLIMATION IN VACUO.
J Immunol. 1965 Mar;94:395-400.
2
Studies on an attenuated measles-virus vaccine. I. Development and preparations of the vaccine: technics for assay of effects of vaccination.减毒麻疹病毒疫苗的研究。I. 疫苗的研发与制备：疫苗接种效果的检测技术
N Engl J Med. 1960 Jul 28;263:153-9. doi: 10.1056/NEJM196007282630401.
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Hemagglutination and hemagglutination-inhibition with measles virus.麻疹病毒的血凝及血凝抑制反应
Virology. 1961 Jan;13:139-41. doi: 10.1016/0042-6822(61)90042-3.
4
Adaptation of measles virus to the chorio-allantoic membrane of chicken embryos in ovo.麻疹病毒在鸡胚卵内对绒毛尿囊膜的适应性
Nature. 1966 Jun 18;210(5042):1233-5. doi: 10.1038/2101233a0.
5
Measles vaccines.
Br Med Bull. 1969 May;25(2):153-8. doi: 10.1093/oxfordjournals.bmb.a070685.