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一种内耳毛细胞将机械能转换为一系列调制动作电位的机制。

A mechanism by which the hair cells of the inner ear transduce mechanical energy into a modulated train of action potentials.

作者信息

Malcolm R

出版信息

J Gen Physiol. 1974 Jun;63(6):757-72. doi: 10.1085/jgp.63.6.757.

Abstract

Physical models of the hair cells of the inner ear were built and analyzed. These models suggest that a straightforward physical process is capable of modulating the electrical resistance of the hair cell. Strong evidence in the literature indicates that such a change in resistance would modulate an otherwise steady electrical current which flows across the hair cell. This would cause the resting potential of the hair cell to change in a systematic fashion, eventually giving rise to the modulated train of action potentials in the neurons leading from the hair cell to the central nervous system.

摘要

内耳毛细胞的物理模型已被构建并分析。这些模型表明,一个简单的物理过程能够调节毛细胞的电阻。文献中的有力证据表明,这种电阻变化会调节原本稳定的流过毛细胞的电流。这将导致毛细胞的静息电位以系统的方式发生变化,最终在从毛细胞通向中枢神经系统的神经元中产生动作电位的调制序列。

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本文引用的文献

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HEARING.听力
Annu Rev Physiol. 1964;26:453-80. doi: 10.1146/annurev.ph.26.030164.002321.
3
DC potentials of the membranous labyrinth.膜迷路的直流电位
Am J Physiol. 1958 Apr;193(1):203-6. doi: 10.1152/ajplegacy.1958.193.1.203.
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Biophysics and physiology of the inner ear.内耳的生物物理学与生理学
Physiol Rev. 1957 Jan;37(1):1-49. doi: 10.1152/physrev.1957.37.1.1.
6
7
Origin of summating potential.
J Acoust Soc Am. 1966 Dec;40(6):1405-13. doi: 10.1121/1.1910240.

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