Bang F B
Infect Immun. 1974 Jun;9(6):1057-61. doi: 10.1128/iai.9.6.1057-1061.1974.
The course of an infection apparently caused by a filterable virus of the blood of the shore crab. Carcinus maenas, has been experimentally studied in this host both at Roscoff, France. where it was originally found, and at Woods Hole, Mass., where the local species was also found susceptible. Although a portion of the infected animals die with the symptoms of inadequate blood clotting, recovery of this function occurred promptly in about two-thirds of the animals. Half of the animals that recovered this function did so within 4 to 6 days. Recovery was not accompanied by disappearance of the virus from the whole blood. In tests done as late as 40 days after recovery, virus was still present. Autointerference was demonstrated after acute infection. It was found in the serum of animals with manifest disease on all days tested and in whole blood of animals taken more than 2 days after the clotting defect appeared. It was not demonstrable within the whole blood within the first 2 days of disease. The role of this in the recovery phenomenon is discussed.
一种显然由可滤过性病毒引起的感染病程，该病毒存在于滨蟹（Carcinus maenas）的血液中。我们在法国罗斯科夫（该病毒最初在此被发现）以及美国马萨诸塞州伍兹霍尔（当地物种也被发现易感），对这种宿主的感染病程进行了实验研究。尽管一部分受感染动物会因血液凝固功能不足的症状而死亡，但约三分之二的动物血液凝固功能迅速恢复。恢复该功能的动物中有一半在4至6天内恢复。恢复过程中病毒并未从全血中消失。在恢复后40天进行的测试中，病毒仍然存在。急性感染后出现了自身干扰现象。在所有测试日患有明显疾病的动物血清中以及在凝血缺陷出现后2天以上采集的动物全血中均发现了自身干扰现象。在疾病的前两天内，全血中未检测到自身干扰现象。文中讨论了其在恢复现象中的作用。
