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[乳腺癌和宫颈癌原发及转移淋巴结中的有丝分裂情况]

[Mitotic conditions in primary and metastatic nodes of breast and cervix cancer].

作者信息

Ermolenko L M

出版信息

Arkh Patol. 1979;41(8):50-3.

PMID:485886
Abstract

The results of the study on the mitotic regimen (mitotic activity ratios of mitosis phases and percent of pathological mitoses) in primary and metastatic nodes of the tumour by the example of mammary gland and cervical carcinoma are presented. A similarity in the mitotic regimen in primary and metastatic nodes of the tumour was observed which was manifested in a high level of mitotic activity predominance of metaphases over other phases of mitosis, the occurrence of similar pathological forms of mitosis. The difference between the mitotic regimen in the primary and metastatic nodes consisted in an increase in the latter of the number of pathological mitoses mostly at the expence of K-mitoses. Three-group metaphase typical of cervical carcinoma was found in all metastatic nodes of the squamous cell carcinoma of the cervix and may probably serve as a peculiar "marker" of tumours of this localization.

摘要

本文以乳腺癌和宫颈癌为例,展示了对肿瘤原发灶和转移灶有丝分裂情况(有丝分裂各期的有丝分裂活性比率及病理性有丝分裂百分比)的研究结果。观察到肿瘤原发灶和转移灶的有丝分裂情况具有相似性,表现为有丝分裂活性水平较高,中期在有丝分裂其他阶段中占优势,出现相似的病理性有丝分裂形式。原发灶和转移灶有丝分裂情况的差异在于,转移灶中病理性有丝分裂数量增加,主要以K型有丝分裂为代价。在宫颈鳞状细胞癌的所有转移灶中均发现了典型的宫颈癌三组中期,这可能是该部位肿瘤的一种特殊“标志物”。

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