• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过冷冻断裂技术研究依他尼酸处理后豚鼠血管纹的细胞膜改变。

Cell membrane alterations in the stria vascularis of the guinea pig after ethacrynic acid treatment studied by freeze-fracture.

作者信息

Forge A

出版信息

Arch Otorhinolaryngol. 1979;224(1-2):149-52. doi: 10.1007/BF00455240.

DOI:10.1007/BF00455240
PMID:485943
Abstract

A freeze-fracture examination of the stria vascularis during the first 2 h after injection of ethacrynic acid was performed. This showed a re-distribution of the particles on the membrane fracture faces of both marginal and intermediate cells. As oedematous spaces developed, particle-poor, vesicle-like structures were found associated with both cell types. The tight junctions at the apices of the marginal cells and around basal cells were unaffected.

摘要

在注射依他尼酸后的最初2小时内,对血管纹进行了冷冻断裂检查。结果显示,边缘细胞和中间细胞的膜断裂面上的颗粒发生了重新分布。随着水肿间隙的形成,在这两种细胞类型中均发现了颗粒稀少的囊泡样结构。边缘细胞顶端和基底细胞周围的紧密连接未受影响。

相似文献

1
Cell membrane alterations in the stria vascularis of the guinea pig after ethacrynic acid treatment studied by freeze-fracture.通过冷冻断裂技术研究依他尼酸处理后豚鼠血管纹的细胞膜改变。
Arch Otorhinolaryngol. 1979;224(1-2):149-52. doi: 10.1007/BF00455240.
2
Freeze-fracture studies of the stria vascularis following administration of ethacrynic acid to guinea pigs.
Scand Audiol Suppl. 1981;14 Suppl:173-83.
3
Gap junctions in the stria vascularis and effects of ethacrynic acid.
Hear Res. 1984 Feb;13(2):189-200. doi: 10.1016/0378-5955(84)90108-4.
4
The endolymphatic surface of the stria vascularis in the guinea-pig and the effects of ethacrynic acid as shown by scanning electron microscopy.豚鼠血管纹的内淋巴表面及依他尼酸作用的扫描电镜观察
Clin Otolaryngol Allied Sci. 1980 Apr;5(2):87-95. doi: 10.1111/j.1365-2273.1980.tb01633.x.
5
Changes of the stria vascularis induced by ethacrynic acid.
Auris Nasus Larynx. 1978;5(1):1-16. doi: 10.1016/s0385-8146(78)80002-9.
6
A tubulo-cisternal endoplasmic reticulum system in the potassium transporting marginal cells of the stria vascularis and effects of the ototoxic diuretic ethacrynic acid.
Cell Tissue Res. 1982;226(2):375-87. doi: 10.1007/BF00218367.
7
Structural abnormalities in the stria vascularis following chronic gentamicin treatment.慢性庆大霉素治疗后血管纹的结构异常。
Hear Res. 1985;20(3):233-44. doi: 10.1016/0378-5955(85)90028-0.
8
Ultrastructure in the stria vascularis of the guinea pig following intraperitoneal injection of ethacrynic acid.
Acta Otolaryngol. 1981 Nov-Dec;92(5-6):439-57. doi: 10.3109/00016488109133283.
9
Comparison of the effects of furosemide and ethacrynic acid upon the cochlear function in the guinea pig.
Scand Audiol Suppl. 1981;14 Suppl:63-9.
10
Cholesterol distribution in cells of the stria vascularis of the mammalian cochlea and some effects of ototoxic diuretics.胆固醇在哺乳动物耳蜗血管纹细胞中的分布及耳毒性利尿剂的一些作用。
J Cell Sci. 1985 Nov;79:181-97. doi: 10.1242/jcs.79.1.181.

本文引用的文献

1
Intercellular junctions in the vascular stria and spiral ligament.
J Ultrastruct Res. 1975 Dec;53(3):284-97. doi: 10.1016/s0022-5320(75)80030-x.
2
[Intercellular junctions in the guinea pig stria vascularis as shown by freeze-etching (author's transl)].豚鼠血管纹的细胞间连接:冷冻蚀刻显示(作者译)
Anat Embryol (Berl). 1975 Aug 9;147(2):189-201. doi: 10.1007/BF00306733.
3
Ethacrynic acid ototoxicity as a general model in cochlear pathology.
Adv Otorhinolaryngol. 1977;22:81-9. doi: 10.1159/000399491.
4
Production and role of inner ear fluid.
Prog Neurobiol. 1975;5(4):337-62. doi: 10.1016/0301-0082(75)90015-5.
5
Effect of ethacrynic acid, furosemide, and ouabain upon the endolymphatic potential and upon high energy phosphates of the stria vascularis.依他尼酸、呋塞米和哇巴因对血管纹内淋巴电位及高能磷酸化合物的影响。
Laryngoscope. 1978 Jan;88(1 Pt 1):12-37. doi: 10.1002/lary.1978.88.1.12.
6
Freeze-fracture electron microscopy: relationship of membrane structural features to transport physiology.冷冻断裂电子显微镜术:膜结构特征与转运生理学的关系
Am J Physiol. 1977 Feb;232(2):F77-83. doi: 10.1152/ajprenal.1977.232.2.F77.
7
Alterations in membrane-associated particle distribution during antidiuretic challenge in frog urinary bladder epithelium.蛙膀胱上皮抗利尿刺激过程中膜相关颗粒分布的变化。
Biophys J. 1976 Jun;16(6):627-39. doi: 10.1016/S0006-3495(76)85717-7.