高胆固醇血症。用考来烯胺治疗，考来烯胺是一种胆汁酸螯合剂。
Hypercholesteremia. Treatment with cholestyramine, a bile acid sequestering resin.
作者信息
Casdorph H R
出版信息
Calif Med. 1967 Apr;106(4):293-5.
Abstract
The results of administration of cholestyramine to 19 patients for periods of two to 21 months are reported. All patients consistently taking the drug obtained a significant reduction in the serum cholesterol. The average reduction was 26 per cent and the range was from 16 to 52 per cent. Cholestyramine acts as a bile acid sequestering resin, causing an increased loss of bile salts (cholates) in the stool. The drug acts by increasing the normal excretory pathway for cholesterol.
摘要
报告了对19名患者使用消胆胺治疗两至21个月的结果。所有持续服用该药物的患者血清胆固醇均显著降低。平均降低26%，范围为16%至52%。消胆胺作为一种胆汁酸螯合树脂，导致粪便中胆盐（胆酸）损失增加。该药物通过增加胆固醇的正常排泄途径起作用。
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Hypercholesteremia. Treatment with cholestyramine, a bile acid sequestering resin.高胆固醇血症。用考来烯胺治疗，考来烯胺是一种胆汁酸螯合剂。
Calif Med. 1967 Apr;106(4):293-5.
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本文引用的文献
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CHOLESTYRAMINE RESIN THERAPY FOR HYPERCHOLESTEREMIA: CLINICAL AND METABOLIC STUDIES.考来烯胺树脂治疗高胆固醇血症：临床与代谢研究
JAMA. 1965 Apr 26;192:289-93. doi: 10.1001/jama.1965.03080170017004.
2
Plasma cholesterol lowering action of bile acid binding polymers in experimental animals.胆汁酸结合聚合物在实验动物中的血浆胆固醇降低作用。
J Lipid Res. 1960 Oct;1:469-73.
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The disposition of orally administered cholestyraminec14.口服消胆胺C14的处置情况。
Proc Soc Exp Biol Med. 1965 Oct;120(1):91-3.
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