Keczkes K, Bilimoria S, Piercy D M
Br J Dermatol. 1979 Aug;101(2):211-7. doi: 10.1111/j.1365-2133.1979.tb05609.x.
A 45-year-old woman is reported with a history of recurrent bacterial infections since childhood; at the age of 37 years she developed recurrent ulcerated lesions around her mouth, in the groins and buttocks, which histologically contained small, non-caseating granulomas. A year latter when being treated for empyema, she was found to have common variable hypogammaglobulinaemia. Three years after this she developed a megaloblastic anaemia of vitamin B12-deficiency type.
据报道，一名45岁女性自幼有反复细菌感染史；37岁时，她在口腔周围、腹股沟和臀部出现反复溃疡病变，组织学检查显示有小的非干酪样肉芽肿。一年后，在治疗脓胸时，发现她患有常见变异型低丙种球蛋白血症。此后三年，她出现了维生素B12缺乏型巨幼细胞贫血。
