Miannik Ia Kh, Tumanian V G
Biofizika. 1979 Sep-Oct;24(5):940-2.
Coordinates of water molecules for B-form of DNA (19 molecules) were determined by the methods of Fourier- and difference Fourier-synthesis. There was shown the strong hydration of the major groove in comparison with the minor one; and one may suppose the different hydration mechanisms for two grooves. There was found water following symmetry of DNA itself and water transforming by the symmetry of cell. Some assumption were made on the different functional properties of grooves of DNA in connection with hydration and also on the character of water dynamics.
采用傅里叶合成法和差傅里叶合成法确定了B型DNA（19个分子）中水分子的坐标。结果表明，与小沟相比，大沟的水化作用更强；由此可以推测两条沟的水化机制不同。发现了遵循DNA自身对称性的水以及因细胞对称性而发生转变的水。基于水化作用对DNA沟的不同功能特性以及水动力学特征做出了一些假设。
