用于快速调查产生抗生素和其他代谢产物的微生物种群的生物自显影技术。
Bioautographic technique for a rapid survey of microbial populations for the production of antibiotics and other metabolites.
作者信息
Meyers E, Smith D A, Donovick R
出版信息
Appl Microbiol. 1968 Jan;16(1):10-2. doi: 10.1128/am.16.1.10-12.1968.
A method is described for the detection of microorganisms capable of producing antibiotics or other metabolites. The microbial population under study was bioautographed against any desired indicator organism. This was easily accomplished by lifting the entire agar layer out of a petri dish on which the microbial population was grown and transferring it to an agar surface seeded with an indicator organism. The use of this technique in the search for metabolites other than antibiotics is pointed out. The advantages of the method, over previously reported methods, are discussed.
描述了一种检测能够产生抗生素或其他代谢产物的微生物的方法。将所研究的微生物群体与任何所需的指示生物进行生物显影。这很容易实现，即将整个琼脂层从培养有微生物群体的培养皿中取出，并将其转移到接种有指示生物的琼脂表面。指出了该技术在寻找抗生素以外的代谢产物方面的应用。讨论了该方法相对于先前报道方法的优点。
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