核糖核苷和脱氧核糖核苷分解代谢存在缺陷的大肠杆菌突变体。
Mutants of Escherichia coli defective in ribonucleoside and deoxyribonucleoside catabolism.
作者信息
Karlström O
出版信息
J Bacteriol. 1968 Mar;95(3):1069-77. doi: 10.1128/jb.95.3.1069-1077.1968.
Abstract
From Escherichia coli B, mutants were prepared that lacked the enzymes adenosine deaminase, cytidine deaminase, and purine nucleoside phosphorylase. In each case, the mutant lacked enzyme activity for both ribonucleoside and deoxyribonucleoside. Mutants lacking purine nucleoside phosphorylase lost the capacity to cleave the nucleosides of adenine, guanine, and hypoxanthine.
摘要
从大肠杆菌B中制备了缺乏腺苷脱氨酶、胞苷脱氨酶和嘌呤核苷磷酸化酶的突变体。在每种情况下，突变体对于核糖核苷和脱氧核糖核苷都缺乏酶活性。缺乏嘌呤核苷磷酸化酶的突变体失去了切割腺嘌呤、鸟嘌呤和次黄嘌呤核苷的能力。
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