用于鉴定新型隐球菌的荧光抗体试剂。
Fluorescent-antibody reagent for the identification of Cryptococcus neoformans.
作者信息
Pidcoe V, Kaufman L
出版信息
Appl Microbiol. 1968 Feb;16(2):271-5. doi: 10.1128/am.16.2.271-275.1968.
Abstract
A sensitive and diagnostically applicable conjugate for the rapid and accurate detection and identification of Cryptococcus neoformans has been developed. C. neoformans rabbit antisera were produced by 14 daily intravenous injections of 36 million cells for a total dosage of approximately 500 million cells. Cross-staining reactions with species of Cryptococcus other than C. neoformans, as well as with Candida species, were eliminated by adsorption of the C. neoformans conjugate with cells of C. diffluens and C. krusei.
摘要
已开发出一种灵敏且适用于诊断的共轭物，用于快速准确地检测和鉴定新型隐球菌。通过每天静脉注射3600万个细胞，连续注射14天，总剂量约为5亿个细胞，制备了新型隐球菌兔抗血清。通过用浅白隐球菌和克鲁斯念珠菌的细胞吸附新型隐球菌共轭物，消除了与新型隐球菌以外的隐球菌属物种以及念珠菌属物种的交叉染色反应。
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Am J Clin Pathol. 1960 Jul;34:52-6. doi: 10.1093/ajcp/34.1.52.
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SEROLOGICAL CHARACTERIZATION OF PATHOGENIC FUNGI BY MEANS OF FLUORESCENT ANTIBODIES. I. ANTIGENIC RELATIONSHIPS BETWEEN YEAST AND MYCELIAL FORMS OF HISTOPLASMA CAPSULATUM AND BLASTOMYCES DERMATITIDIS.用荧光抗体对致病性真菌进行血清学鉴定。I. 荚膜组织胞浆菌和皮炎芽生菌酵母型与菌丝型之间的抗原关系。
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