Paling M R
Br J Radiol. 1979 Aug;52(620):620-3. doi: 10.1259/0007-1285-52-620-620.
This study shows that contrast enhancement of cerebral lesions can be adequately achieved with a bolus injection of 60 ml of sodium iothalamate 70%. While the infusion of a larger dose of contrast agent increases quantitatively the level of enhancement of a variety of lesions, this method of examination does not appear to provide any more useful diagnostic information, and it introduces added and unnecessary inconvenience, cost and potential hazard.
本研究表明，通过静脉快速推注60毫升70%的碘他拉酸钠可充分实现脑病变的对比增强。虽然输注更大剂量的造影剂会使各种病变的增强水平在数量上增加，但这种检查方法似乎并未提供更多有用的诊断信息，反而带来了额外且不必要的不便、成本和潜在风险。
