Van De Poll N E, Van Dis H
Brain Res Bull. 1979 Jul-Aug;4(4):505-11. doi: 10.1016/0361-9230(79)90035-2.
The effects of bilateral radiofrequency lesions in various parts of the medial preoptic area (mPOA) and anterior hypothalamus (AH) on masculine and hormone induced feminine sexual behavior was studied in male rats. Anatomical as well as statistical analysis of the extent and location of the lesions and the consequent behavioral changes indicated that different parts of the mPOA-AH continuum are involved in masculine and feminine sexual behavior in different ways. Bilateral destruction at the transition of the mPOA and AH resulted in a large reduction of masculine sexual activity while lesions concentrated in the AH slightly facilitated feminine sexual behavior in males. These results are consistent with the notion that the mPOA-AH continuum is divided into anatomically and functionally different parts.
研究了内侧视前区（mPOA）和下丘脑前部（AH）不同部位的双侧射频损伤对雄性大鼠雄性性行为和激素诱导的雌性性行为的影响。对损伤范围和位置以及随之而来的行为变化进行的解剖学和统计学分析表明，mPOA-AH连续体的不同部分以不同方式参与雄性和雌性性行为。mPOA和AH交界处的双侧破坏导致雄性性行为大幅减少，而集中在AH的损伤则略微促进了雄性的雌性性行为。这些结果与mPOA-AH连续体分为解剖学和功能上不同部分的观点一致。
