Kraicer J
Can J Physiol Pharmacol. 1979 Jul;57(7):748-50. doi: 10.1139/y79-113.
Acetylcholine (1 micromol/L--1 mmol/L) has been reported to stimulate growth hormone release from perifused bovine pituitary slices. We have carried out studies using the perifused pars distalis of the rat adenohypophysis to see whether a similar response is observed. Neither acetylcholine, acetylcholine with eserine, nor carbamylcholine, at concentrations of 10(-9), 10(-6), and 10(-3) M. stimulated the release of growth hormone. Thus we could not demonstrate a similar reponse to acetylcholine in the pars distalis of the rat adenohypophysis as reported in the bovine gland.
据报道,乙酰胆碱(1微摩尔/升 - 1毫摩尔/升)可刺激经灌流的牛垂体切片释放生长激素。我们利用大鼠腺垂体远侧部灌流进行了研究,以观察是否能观察到类似的反应。浓度为10^(-9)、10^(-6)和10^(-3) M的乙酰胆碱、乙酰胆碱与毒扁豆碱合用以及氨甲酰胆碱,均未刺激生长激素的释放。因此,我们无法证明大鼠腺垂体远侧部对乙酰胆碱的反应与牛腺垂体中所报道的类似。