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口服避孕药所致头痛与子宫内膜小动脉发育之间的关系

Relation between headaches from oral contraceptives and development of endometrial arterioles.

作者信息

Grant E C

出版信息

Br Med J. 1968 Aug 17;3(5615):402-5. doi: 10.1136/bmj.3.5615.402.

Abstract

The incidence of headaches during the first year on oral cotraceptives corrleates closely with the incidence of well-developed arterioles in endometrial biopsy specimens. This relationship appears to depend on the ratio between progestogenic and oestrogenic components of the pill as well as the particular steroids. Therefore endometrial biopsies are useful for assessing the vascular response to an oral contraceptive and also provide a short cut to clinical evaluation of new formulations.

摘要

口服避孕药第一年头痛的发生率与子宫内膜活检标本中发育良好的小动脉的发生率密切相关。这种关系似乎取决于避孕药中孕激素和雌激素成分的比例以及特定的类固醇。因此,子宫内膜活检有助于评估口服避孕药引起的血管反应,也为新配方的临床评估提供了一条捷径。

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本文引用的文献

1
Clinical trials of oral contraceptives.口服避孕药的临床试验。
Br Med J. 1961 Nov 4;2(5261):1179-83. doi: 10.1136/bmj.2.5261.1179.
2
"Anovlar" as an oral contraceptive.“Anovlar”作为一种口服避孕药。
Br Med J. 1962 Jul 14;2(5297):75-9. doi: 10.1136/bmj.2.5297.75.
4
Cerebral arterial insufficiency and oral contraceptives.脑动脉供血不足与口服避孕药
Br Med J. 1967 Mar 25;1(5542):726-9. doi: 10.1136/bmj.1.5542.726.
5
Oral contraceptives and cerebral arterial occlusion.口服避孕药与脑动脉闭塞
Br Med J. 1965 Nov 13;2(5471):1164-6. doi: 10.1136/bmj.2.5471.1164.
6
Oral contraceptives and neuro-ophthalmologic interest.
Arch Ophthalmol. 1965 Nov;74(5):628-40. doi: 10.1001/archopht.1965.00970040630009.

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