Dames W, Joó F, Wolff J R
Exp Brain Res. 1979 Jul 2;36(2):259-64. doi: 10.1007/BF00238909.
A method is described for localized microapplication of drugs into nervous tissue of freely moving rats. Fairly constant release of material was observed over a period of more than three weeks. The amount of substance released was small because the rate of release was determined largely by diffusion rather than by mass movement of solution.