Honoré L H
Fertil Steril. 1979 Oct;32(4):401-2. doi: 10.1016/s0015-0282(16)44294-9.
A retrospective study of 83 patients with pathologically documented tubal ectopic pregnancy demonstrated a statistically significant association (P less than 0.005) between prior spontaneous abortion and ectopic pregnancy. In this population with a low incidence of chronic salpingitis, it is suggested that delayed (post-midcycle) ovulation, causing preovulatory over-ripeness of the ovum, may be the common underlying etiologic factor. The clinical significance of this finding is also briefly discussed.
一项对83例经病理证实为输卵管异位妊娠患者的回顾性研究表明,既往自然流产与异位妊娠之间存在统计学上的显著关联(P小于0.005)。在慢性输卵管炎发病率较低的这一人群中,提示排卵延迟(月经周期中期之后)导致卵子排卵前过度成熟,可能是共同的潜在病因。还简要讨论了这一发现的临床意义。