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[离子主动转运抑制剂对乳腺实质受体的自发和诱发电活动的影响]

[Effect of inhibitors of the active transport of ions on the spontaneous and evoked electrical activity of parenchymal mammary gland receptors].

作者信息

Grachev I I, Alekseev N P, Khatazhukova E I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1979 Sep;65(9):1276-84.

PMID:488455
Abstract

In the potassium-free saline spontaneous activity of the mammary gland parenchyma receptor increased within first 30--40 min., then decreased and, finally, ceased. Sensitivity of the receptor to the mechanical stimuli decreased gradually. After washing in normal saline the evoked and spontaneous activities recovered. Ouabain (5 . 10(-5)--10(-4) g/ml) exerted an effect similar to that of the potassium--free solution except that the impulse activity could not be restored by the washing in physiological saline.

摘要

在无钾盐溶液中,乳腺实质感受器的自发活动在最初30 - 40分钟内增强,随后减弱,最终停止。感受器对机械刺激的敏感性逐渐降低。用生理盐水冲洗后,诱发活动和自发活动恢复。哇巴因(5×10⁻⁵ - 10⁻⁴克/毫升)产生的作用与无钾溶液相似,只是用生理盐水冲洗后冲动活动无法恢复。

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