Like A A, Chick W L
Science. 1969 Feb 28;163(3870):941-3. doi: 10.1126/science.163.3870.941.
Successful expansion of the islet cell mass occurs in genetically diabetic mice (C57 Bl/Ks-dbdb) following a period of dietary restriction, in the absence of a population of precursor cells. Differentiated cells that synthesize insulin retain the capability of undergoing mitotic division.
在缺乏前体细胞群体的情况下,经过一段时间的饮食限制后,遗传性糖尿病小鼠(C57 Bl/Ks-dbdb)的胰岛细胞团成功扩增。合成胰岛素的分化细胞保留了进行有丝分裂的能力。