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比较两周和六周治疗对复发性尿路感染疗效的对照试验。

Controlled trial comparing effect of two and six weeks' treatment in recurrent urinary tract infection.

作者信息

Kincaid-Smith P, Fairley K F

出版信息

Br Med J. 1969 Apr 19;2(5650):145-6. doi: 10.1136/bmj.2.5650.145.

DOI:10.1136/bmj.2.5650.145
PMID:4888353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1982964/
Abstract

Patients with recurrent urinary tract infection were allocated at random to two weeks' or six weeks' treatment with an appropriate antibacterial drug. There was no difference in the results achieved by the two different periods of treatment as judged by the presence of infection in the urine one week and six weeks after treatment was stopped.The urine was clear of infection in a higher percentage of patients following a course of nitrofurantoin than following a course of ampicillin, but the difference was not significant.

摘要

复发性尿路感染患者被随机分配接受为期两周或六周的适当抗菌药物治疗。根据治疗停止后一周和六周时尿液中是否存在感染来判断,两种不同疗程的治疗效果并无差异。服用呋喃妥因疗程后的患者尿液清除感染的比例高于服用氨苄西林疗程后的患者,但差异不显著。

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Controlled trial comparing effect of two and six weeks' treatment in recurrent urinary tract infection.比较两周和六周治疗对复发性尿路感染疗效的对照试验。
Br Med J. 1969 Apr 19;2(5650):145-6. doi: 10.1136/bmj.2.5650.145.
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Extended therapy in patients with established urinary tract infection.
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引用本文的文献

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Single-dose antibiotic treatment: a new approach to lower urinary tract infections in primary care.单剂量抗生素治疗:初级保健中降低下尿路感染的新方法。
Can Fam Physician. 1981 Jan;27:143-5.
2
Symptomless bacteriuria.无症状菌尿
Br Med J. 1969 Jul 12;3(5662):69-70.
3
Resistant urinary infections resulting from changes in resistance pattern of faecal flora induced by sulphonamide and hospital environment.由磺胺类药物和医院环境引起的粪便菌群耐药模式改变导致的耐药性泌尿系统感染。
Br Med J. 1970 Aug 8;3(5718):305-9. doi: 10.1136/bmj.3.5718.305.
4
Duration of treatment for urinary tract infections in children.儿童尿路感染的治疗时长。
Br Med J. 1975 Jul 12;3(5975):65-6. doi: 10.1136/bmj.3.5975.65.
5
Common bacterial infections in infancy and childhood. 7. Neonatal infections.婴幼儿常见细菌感染。7. 新生儿感染。
Drugs. 1978 Sep;16(3):226-37. doi: 10.2165/00003495-197816030-00005.
6
Treatment of urinary tract infection with a single dose of trimethoprim-sulfamethoxazole.用单剂量甲氧苄啶-磺胺甲恶唑治疗尿路感染。
Can Med Assoc J. 1978 Mar 4;118(5):551-2.

本文引用的文献

1
Long-term treatment of pyelonephritis and other urinary tract infections with a new combination of sulfanilamides.用一种新的磺胺类药物组合对肾盂肾炎和其他尿路感染进行长期治疗。
J Urol. 1962 Mar;87:220-9. doi: 10.1016/S0022-5347(17)64945-0.
2
CHEMOTHERAPY IN ACUTE AND CHRONIC PYELONEPHRITIS. A TWO-YEAR CLINICAL, BACTERIOLOGICAL, AND FUNCTIONAL FOLLOW-UP.
Lancet. 1963 Sep 21;2(7308):601-3. doi: 10.1016/s0140-6736(63)90395-7.
3
Treatment of urinary-tract infections with amphicillin. A clinical trial.氨苄青霉素治疗尿路感染。一项临床试验。
Lancet. 1962 Jan 20;1(7221):130-3. doi: 10.1016/s0140-6736(62)91132-7.
4
The problem of pyelonephritis. A four-year study of a pyelonephritis unit.肾盂肾炎问题。对一个肾盂肾炎治疗单元的四年研究。
Practitioner. 1966 Jun;196(176):800-10.
5
Long-acting sulfonamide (Sulfamethoxydiazine) in the therapy of chronic urinary infections.长效磺胺(磺胺甲氧嗪)在慢性泌尿系统感染治疗中的应用
J Am Geriatr Soc. 1966 Apr;14(4):380-7. doi: 10.1111/j.1532-5415.1966.tb05600.x.
6
Long-term antibacterial treatment of chronic pyelonephritis.慢性肾盂肾炎的长期抗菌治疗。
Acta Med Scand. 1967 Jan;181(6):641-53. doi: 10.1111/j.0954-6820.1967.tb07982.x.